Publications

2022

Klawitter, F., Oppitz, M. C., Goettel, N., Berger, M. M., Hodgson, C., Weber-Carstens, S., Schaller, S. J., & Ehler, J. (2022). A Global Survey on Diagnostic, Therapeutic and Preventive Strategies in Intensive Care Unit-Acquired Weakness. Medicina (Kaunas, Lithuania), 58(8), 1068.

Klinkmann G, Wild T, Heskamp B, et al. Extracorporeal immune cell therapy of sepsis: ex vivo results. Intensive Care Med Exp. 2022;10(1):26.

Klawitter F, Walter U, Patejdl R, Endler J, Reuter DA, Ehler J. Sonographic Evaluation of Muscle Echogenicity for the Detection of Intensive Care Unit-Acquired Weakness: A Pilot Single-Center Prospective Cohort Study. Diagnostics (Basel). 2022;12(6):1378.

Ehler J, Terpe F, Chao CM. Surfactant Protein C-Mangel beim Neugeborenen. Dtsch Arztebl Int 2022; in print

Klawitter F, Schaller SJ, Söhle M, Reuter DA, Ehler J. Intensive Care Unit – Acquired Weakness. Eine bundesweite Umfrage zu Diagnostik, Monitoring und Therapiestrategien auf deutschen Intensivstationen. Anaesthesist. 2022 Feb 2. doi: 10.1007/s00101-022-01089-9.

Klinkmann G, Doss F, Goudeva L, et al. Prolonged storage of purified granulocyte concentrates: Introduction of a new purification method. Transfusion. 2022;62(1):194-204.

Schiller B, Radke M, Hauenstein C, Müller C, Spang C, Reuter DA, Däbritz J, Ehler J. Large Duodenal Hematoma Causing an Ileus after Endoscopic Duodenal Biopsy in a 6-Year-Old Child: A Case Report. Medicina (Kaunas) 2022,58,12.

Klinkmann G, Ehler J (2022). Neurokognitives Defizit nach Septischer Enzephalopathie. In: Eckart J, Weigand M, Briegel J (Hrsg.) Handbuch Intensivpflege, Erg.-Lfg. ecomed Medizin, Landsberg; in print

2021

Müller-Knapp M, Classen CF, Knöfler R, Spang C, Hauenstein C, Heinrich T, Gabriel FLP, Däbritz J, Reuter DA, Ehler J. Coexistence of antithrombin deficiency and suspected inferior vena cava atresia in an adolescent and his mother – case report and clinical implications. Thrombosis Journal 2021;19:105

Patejdl R, Klawitter F, Walter U,Zanaty K, Schwandner F, Sellmann T, Porath K, Ehler J. A novel ex vivo model for critical illness neuromyopathy using freshly resected human colon smooth muscle. Sci Rep. 2021 Dec 20;11(1):24249.

Bajorat R, Kurth J, Stenzel J, Vollmar B, Krause BJ, Reuter DA, Schuerholz T, Bergt S. Early Post-ischemic Brain Glucose Metabolism Is Dependent on Function of TLR2: a Study Using [18F] F-FDG PET-CT in a Mouse Model of Cardiac Arrest and Cardiopulmonary Resuscitation. Mol Imaging Biol 2021;15:1-13.

Ehler J, Busjahn C, Schürholz T. Which biomarkers for diagnosis and guidance of anti-infection treatment in sepsis? Anästhesist 2021 Nov 12. doi: 10.1007/s00101-021-01067-7.

Klinkmann G, Ehler J (2021). Neurokognitives Defizit nach Septischer Enzephalopathie. In: Eckart J, Weigand M, Briegel J (Hrsg.) Intensivmedizin, Erg.-Lfg. ecomed Medizin, Landsberg (in print)

Ehler J (2021). Unterschätzt? Diagnostik und Konsequenzen der septischen Enzephalopathie. In: Kluge et al. (Hrsg.) DIVI-Jahrbuch 2021/2022, S. 457-462. MWV Medizinisch Wissenschaftliche Verlagsgesellschaft. ISBN: 978-3-95466-651-5.

Müller C, Spang C, Ehler J, Hauenstein C. Iatrogenes intramurales Hämatom des Duodenums nach Gastroskopie beim Kind. Diagnostische und therapeutische Überlegungen. Pädiatrische Praxis 2021;96:83-87

Johannes Ehler, Andreas Klug, Chrisitan Spang, Barbara Wichmann, Sigmone Richter, Jan Däbritz, Daniel A. Reuter. Die Interdisziplinäre Kinder-Intensivstation (iKIT) der Universitätsmedizin Rostock. Ein neues Versorgungskonzept der interdisziplinären Versorgung kritisch kranker Kinder und Jugendlicher. Ärzteblatt Mecklenburg-Vorpommern, Ausgabe 1/2021, 31. Jahrgang, S.30-34.

Blechinger S, Ehler J, Bsteh, G, Winkelmann, A, Leutmezer, F, Meister, S, Santer, A, Hecker, M, Berger, T, Rommer, P, Zettl, UK. Therapeutic plasma exchange in steroid-refractory multiple sclerosis relapses. A retrospective two-center study. Ther Adv Neurol Disord 2021, Vol. 14: 1-8

2020

Ehler J, Reuter DA (2020). Delir und Sedierung – Wie kann ich diagnostizieren? In: Eckart J, Weigand M, Briegel J (Hrsg.) Handbuch der Intensivpflege, Kap. VIII-5.4, 71. Erg.-Lfg. ecomed Medizin, Landsberg.

Ehler J, Reuter DA (2020). Delir und Sedierung – Wie kann ich diagnostizieren? In: Eckart J, Weigand M, Briegel J (Hrsg.) Intensivmedizin, Kap. XIII-26.1, 99. Erg.-Lfg. ecomed Medizin, Landsberg.

Klawitter F, Jager M, Klinkmann G, Saller T, Söhle M, von Möllendorff F, Reuter DA, Ehler J. Sepsis-assoziierte Enzephalopathie – Eine bundesweite Umfrage zu Verfahren der Diagnostik und des Neuromonitorings auf deutschen Intensivstationen. Der Anaesthesist 2020 Sep 24.

Lademann H, Bertsche A, Petzold A, Zack F, Büttner A, Däbritz J, Hauenstein C, Bahn E, Spang C, Reuter D, Warnke P, Ehler J. Acute Disseminated Encephalomyelitis with Seizures and Myocarditis: A Fatal Triad. Medicina2020, 56, 277.

Saller T, Peterss S, Scheiermann P, Eser-Valeri D, Ehler J, Bruegger D, Chappell D, Kofler O, Hagl C, Hofmann-Kiefer K. Natriuretic Peptides as a Prognostic Marker for Delirium in Cardiac Surgery—A Pilot Study. Medicina 2020, 56, 258.

Köhler J, Ehler J, Kreikemeyer B, Bajorat R, Schürholz T, Oehmcke-Hecht S. The synthetic LPS binding peptide 19-2.5 interferes with clotting and prevents degradation of high molecular weight kininogen in plasma. Scientific reports 2020; Apr 28;10(1):7142.

Klinkmann G, Stope MB, Meyer A. Cytokine adsorption as a promising option for septic shock and multiple organ failure due to Candida infection and decompensated type 1 diabetes mellitus. Artif Organs 2020 May;44(5):522-525. 

Kletschkus K, Haralambiev L, Nitsch A,  Pfister F, Klinkmann G, Kramer A, Bekeschus S, Mustea A, Stope M. The Application of a Low-temperature Physical Plasma Device Operating Under Atmospheric Pressure Leads to the Production of Toxic NO2. Anticancer research 2020.

Klawitter F, Ehler J, Reuter DA, Patejdl R. Relations between early neuromuscular alterations, gastrointestinal dysfunction and clinical nutrition in critically ill patients: an exploratory single-center cohort study. Neurocrit Care 2020 Apr 3.

Ehler J, Petzold A, Sharshar T, Ely EW, Saller T. Biomarker panel to differentiate brain injury from brain dysfunction in patients with sepsis-associated encephalopathy. Crit Care Med 2020; May;48(5):e436-e437.

Klawitter F, Ehler J. WAKNA-Herbsttreffen 2019, Kongressbericht. Anästh Intensivmed 2020;61:V5–V6.

2019

Saller T, Petzold A, Zetterberg H, Kuhle J, Chappell D, von Dossow V, Klawitter F et al. A case series on the value of tau and neurofilament protein levels to predict and detect delirium in cardiac surgery patients. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2019; 163(3):241–6.

Ehler J, Petzold A, Wittstock M, Kolbaske S, Gloger M, Henschel J et al. Correction: The prognostic value of neurofilament levels in patients with sepsis-associated encephalopathy - A prospective, pilot observational study. PLoS One 2019; 14(2):e0212830.

Ehler J, Petzold A, Wittstock M, Kolbaske S, Gloger M, Henschel J et al. The prognostic value of neurofilament levels in patients with sepsis-associated encephalopathy - A prospective, pilot observational study. PLoS One 2019; 14(1):e0211184.

Ehler J, Saller T, Wittstock M, Rommer PS, Chappell D, Zwissler B et al. Diagnostic value of NT-proCNP compared to NSE and S100B in cerebrospinal fluid and plasma of patients with sepsis-associated encephalopathy. Neurosci Lett 2019; 692:167–73.

Patejdl R, Walter U, Rosener S, Sauer M, Reuter DA, Ehler J. Muscular Ultrasound, Syndecan-1 and Procalcitonin Serum Levels to Assess Intensive Care Unit-Acquired Weakness. Can J Neurol Sci 2019; 46(2):234–42.

2018

Mann T, Zilles K, Klawitter F, Cremer M, Hawlitschka A, Palomero-Gallagher N et al. Acetylcholine Neurotransmitter Receptor Densities in the Striatum of Hemiparkinsonian Rats Following Botulinum Neurotoxin-A Injection. Front Neuroanat 2018; 12:65.

Sauer M, Haubner C, Richter G, Ehler J, Mencke T, Mitzner S et al. Impaired Cell Viability and Functionality of Hepatocytes After Incubation With Septic Plasma-Results of a Second Prospective Biosensor Study. Front Immunol 2018; 9:1448.

Sauer M, Richter G, Altrichter J, Wild T, Doss F, Mencke T et al. Effects of Bioreactor-Oxygenation During Extracorporeal Granulocytes Treatment in Septic Patients. Ther Apher Dial 2018; 22(4):389–98.

2017

Ehler J, Barrett LK, Taylor V, Groves M, Scaravilli F, Wittstock M et al. Translational evidence for two distinct patterns of neuroaxonal injury in sepsis: a longitudinal, prospective translational study. Crit Care 2017; 21(1):262.

Ehler J, Blechinger S, Rommer PS, Koball S, Mitzner S, Hartung H-P et al. Treatment of the First Acute Relapse Following Therapeutic Plasma Exchange in Formerly Glucocorticosteroid-Unresponsive Multiple Sclerosis Patients-A Multicenter Study to Evaluate Glucocorticosteroid Responsiveness. Int J Mol Sci 2017; 18(8).

Sauer M, Doss S, Ehler J, Mencke T, Wagner N-M. Procalcitonin Impairs Liver Cell Viability and Function In Vitro: A Potential New Mechanism of Liver Dysfunction and Failure during Sepsis? Biomed Res Int 2017; 2017:6130725.

Ehler J, Schurholz T. Anasthesiol Intensivmed Notfallmed Schmerzther 2017; 52(4):298–302.

2012-2016

Patejdl R, Winkelmann A, Ehler J, Zettl H, Meister S, Zettl UK. Diagnostic Workup and Treatment of Antibody-Related Encephalomyelitis. Fortschr Neurol Psychiatr 2016; 84(S 02):S88-S91.

Sauer M, Altrichter J, Haubner C, Pertschy A, Wild T, Doss F et al. Bioartificial Therapy of Sepsis: Changes of Norepinephrine-Dosage in Patients and Influence on Dynamic and Cell Based Liver Tests during Extracorporeal Treatments. Biomed Res Int 2016; 2016:7056492.

Ehler J, Schurholz T. Anasthesiol Intensivmed Notfallmed Schmerzther 2016; 51(11-12):676–9.

Ehler J, Koball S, Sauer M, Hickstein H, Mitzner S, Benecke R et al. Therapeutic plasma exchange in glucocorticosteroid-unresponsive patients with Clinically Isolated Syndrome. Ther Apher Dial 2014; 18(5):489–96.

Ehler J, Koball S, Sauer M, Mitzner S, Hickstein H, Benecke R et al. Response to Therapeutic Plasma Exchange as a Rescue Treatment in Clinically Isolated Syndromes and Acute Worsening of Multiple Sclerosis: A Retrospective Analysis of 90 Patients. PLoS One 2015; 10(8):e0134583.

Ehler J, Patejdl R, Junghanss C, Lehmitz R, Pahnke J, Grossmann A et al. Intrathecal large granular lymphocytes as an unusual presentation of a small cell T cell lymphoma. Clin Neurol Neurosurg 2012; 114(7):1102–3.